Pharmacology Women and Men's Health Drugs

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Sample questions from Pharmacology Women and Men's Health Drugs

This material has 90 questions with answers and rationales. Here are the first 5.

1. 1.A client taking warfarin begins a new medication that inhibits hepatic drug-metabolizing enzymes. Which change is the nurse most concerned about?

   • A.The warfarin effect may decrease, raising clotting risk.
   • B.Warfarin will be eliminated unchanged more rapidly.
   • C.Warfarin absorption will stop completely.
   • D.The warfarin effect may increase, raising bleeding risk.

   Rationale: Enzyme inhibition can slow warfarin metabolism, increase its serum concentration, and elevate the INR and bleeding risk. Reduced warfarin effect is more consistent with enzyme induction, not inhibition. These interactions generally do not stop intestinal absorption or cause faster unchanged renal elimination. The nurse should check for interaction-specific guidance and monitor INR and signs of bleeding.

2. 2.A client with a feeding tube is prescribed an extended-release tablet. Which action is appropriate?

   • A.Give the tablet with the feeding and flush the tube afterward.
   • B.Dissolve the tablet in warm water before administration.
   • C.Consult the pharmacist for an appropriate alternative formulation.
   • D.Crush the tablet finely and mix it with the feeding.

   Rationale: Extended-release products should not generally be crushed because doing so can release the dose rapidly and cause toxicity. Dissolving or mixing the product with food does not make crushing safe. Flushing does not prevent altered drug release or tube obstruction. The nurse should verify whether a liquid or immediate-release formulation can be prescribed and how it should be administered.

3. 3.A client with chronic kidney disease is prescribed a medication that is primarily eliminated by the kidneys. Which actions support safe administration? Select all that apply.

   • A.Expect the prescribed dose or dosing interval may need adjustment.
   • B.Assume a normal serum drug level rules out impaired renal elimination.
   • C.Review the client's estimated glomerular filtration rate before administration.
   • D.Clarify the prescription if the dose appears inappropriate for renal function.
   • E.Assess for adverse effects that may indicate drug accumulation.

   Rationale: Reviewing estimated glomerular filtration rate helps identify impaired clearance and supports safe dosing. Monitoring for adverse effects is important because reduced renal elimination can cause accumulation. Dose reduction or a longer interval may be needed, depending on the medication. A normal drug level does not by itself rule out impaired renal function or future accumulation. A potentially inappropriate dose should be clarified rather than administered automatically.

4. 4.A client is prescribed a medication with a narrow therapeutic index. Which plan best supports safe treatment?

   • A.Monitor the recommended serum concentration and assess for therapeutic and toxic effects.
   • B.Use the same dose for every client to avoid concentration fluctuations.
   • C.Wait for symptoms of toxicity before obtaining any laboratory tests.
   • D.Increase the dose whenever the client reports no immediate benefit.

   Answer and rationale are in the full material.

5. 5.During medication reconciliation, which information should the nurse obtain to reduce the risk of medication-related harm? Select all that apply.

   • A.Prescription medications and their actual dosing schedule.
   • B.A list of discontinued medications only, without asking about current use.
   • C.Over-the-counter medicines, vitamins, and herbal products.
   • D.Medication allergies and the reaction to each medication.
   • E.Whether the client sometimes skips, changes, or shares doses.

   Answer and rationale are in the full material.