Lehne's Pharmacology for Nursing Care 12TH Edition Question Bank

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Sample questions from Lehne's Pharmacology for Nursing Care 12TH Edition Question Bank

This material has 90 questions with answers and rationales. Here are the first 5.

1. 1.A client taking an oral medication asks why the prescribed dose is lower than the dose given by injection. Which explanation is most accurate?

   • A.Some orally administered medication is metabolized before reaching systemic circulation.
   • B.Injected medication is subject to greater first-pass metabolism.
   • C.The oral route bypasses the liver.
   • D.Oral medication is always absorbed more rapidly than injected medication.

   Rationale: Some drugs undergo first-pass metabolism in the intestinal wall or liver, reducing the amount that reaches systemic circulation after oral administration. Oral drugs do not bypass the liver, and injected drugs generally avoid first-pass metabolism. Absorption rate varies by drug and route, so the oral route is not always faster.

2. 2.A nurse is teaching a client about safe use of a newly prescribed extended-release tablet. Which instructions should the nurse include? Select all that apply.

   • A.Swallow the tablet whole unless the product instructions say otherwise.
   • B.Take doses at the prescribed intervals.
   • C.Take an extra tablet if the dose seems to wear off early.
   • D.Ask a pharmacist before splitting the tablet.
   • E.Crush the tablet if swallowing is difficult.

   Rationale: Swallowing an extended-release tablet whole helps preserve its designed release pattern. Crushing it can release too much drug at once, and an extra dose risks toxicity. Doses should follow the prescribed schedule, and a pharmacist can verify whether a specific product may be split.

3. 3.Which client is most likely to have a prolonged medication half-life because of reduced drug clearance?

   • A.A client with a superficial skin abrasion
   • B.An older adult with markedly reduced renal function
   • C.A healthy adult with an acute ankle sprain
   • D.A teenager with seasonal allergies

   Rationale: Reduced renal function can slow elimination of drugs or metabolites cleared by the kidneys, prolonging half-life and increasing accumulation risk. The other clients have no stated impairment in drug clearance. Age alone does not determine dosing, but age-associated renal decline warrants assessment.

4. 4.The provider prescribes a medication with a narrow therapeutic index. Which action is most important for safe administration?

   • A.Avoid assessing for adverse effects once the desired response occurs.
   • B.Give the medication only when the client reports symptoms.
   • C.Monitor the client for therapeutic and toxic effects and obtain ordered drug levels.
   • D.Double the next dose if one dose is delayed.

   Answer and rationale are in the full material.

5. 5.At 0900, a nurse discovers that a scheduled 0800 dose was omitted. What should the nurse do first?

   • A.Give two doses at 0900 to catch up.
   • B.Document the dose as administered at 0800.
   • C.Omit all future doses of the medication.
   • D.Assess the client and consult the medication instructions or prescriber about the missed dose.

   Answer and rationale are in the full material.