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HESI A2 Complete Study Guide: Four Core Sections

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Sample questions from HESI A2 Complete Study Guide: Four Core Sections

This material has 20 questions with answers and rationales. Here are the first 5.

  1. 1.A patient is ordered to receive 0.5 grams of a medication. The pharmacy provides the medication in 250 mg tablets. How many tablets should the nurse administer?

    • A.0.5 tablet
    • B.1 tablet
    • C.2 tablets
    • D.4 tablets

    Rationale: First, convert grams to milligrams: 0.5 g * 1000 = 500 mg. Then, divide the desired dose by the dose on hand: 500 mg / 250 mg = 2 tablets. Options A, B, and D are incorrect mathematical calculations.

  2. 2.Which organelle is primarily responsible for the production of Adenosine Triphosphate (ATP)?

    • A.Ribosome
    • B.Lysosome
    • C.Mitochondria
    • D.Golgi apparatus

    Rationale: The mitochondria are known as the powerhouse of the cell because they perform cellular respiration to produce ATP. Ribosomes synthesize proteins, lysosomes digest waste, and the Golgi apparatus packages proteins.

  3. 3.In the human heart, which chamber is responsible for pumping oxygenated blood into the systemic circulation via the aorta?

    • A.Right Atrium
    • B.Right Ventricle
    • C.Left Atrium
    • D.Left Ventricle

    Rationale: The left ventricle receives oxygenated blood from the left atrium and pumps it through the aorta to the rest of the body. The right side of the heart handles deoxygenated blood.

  4. 4.A nurse is reviewing a patient's arterial blood gas (ABG) results and notes a pH of 7.25. How should the nurse interpret this finding?

    • A.Normal
    • B.Alkalosis
    • C.Acidosis
    • D.Neutral

    Answer and rationale are in the full material.

  5. 5.Which of the following is an example of a factual statement rather than an opinion?

    • A.The hospital's new policy is much better than the old one.
    • B.Nurses should always wear blue scrubs.
    • C.The patient's temperature was recorded as 101.2 degrees Fahrenheit.
    • D.The cafeteria food is not very nutritious.

    Answer and rationale are in the full material.

+15 more questions with answers and rationales

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Released October 19, 2026 · Independent original practice and study material.